Blog Posts

Nanome v2.4.0 is now available as an open access early release on Meta Quest. This milestone update brings voice-controlled molecular visualization, multi-frame playback for docking pose analysis, ligand minimization with MMFF94/UFF force fields, and native chemical interaction calculations—all in immersive XR. Designed for computational chemists and drug discovery teams, v2.4 accelerates structure-based drug design workflows with real-time collaboration and intuitive 3D molecular manipulation.

Meta announces free Horizon Managed Services for Quest VR device management starting February 2026. Learn how this impacts computational chemistry, CADD, and drug discovery workflows using Nanome's molecular visualization platform, plus migration options to Android XR

Learn how to set up Boltz-2 for protein structure prediction with MSA and YAML files, plus streamline analysis using Nanome AI's MARA assistant.

Bridging the gap between molecular abstraction and atomic reality: insights for CADD scientists and computational chemists on the precision design revolution. Discover how visualizing peptides and protein structures in 3D is transforming the engineering of GLP-1s, ADCs, and small molecules.

Security update for Nanome VR addressing a Unity engine vulnerability. Learn what’s been fixed, recommended actions for Meta Quest and PC VR users, and how to update Nanome to the latest patched versions for maximum protection.

Nanome v2.3.0 delivers 3D ligand building, web-based VR workspace preview, and precision molecular design tools for drug discovery and computational chemistry

Streamline drug discovery with MARA-Flare integration. Automate protein preparation, pocket detection, and molecular docking from PDB to pose in one workflow.

Overcome the limits of 2D visualization in drug discovery. See how an intuitive XR measurement tool provides precise 3D data for structural biology and CADD

Nanome v2.2.0 delivers powerful new features for scientists analyzing molecular structures in immersive, collaborative settings. Whether you're measuring atomic distances, customizing structural representations, or exploring chemical interactions with teammates, this release deepens your ability to understand complex data intuitively and efficiently.

Nanome v2.1.1 delivers major upgrades to molecular visualization, scene management, and collaborative workflows. Set scene-specific perspectives, enjoy smoother rendering, and experience an improved user interface across the board.

Explore Nanome’s new integration with Cadence’s OpenEye platform, featuring FastROCS molecular search, molecular dynamics trajectory analysis, and cryptic pocket detection—all directly accessible in Nanome XR and MARA to accelerate drug discovery and collaborative molecular design.

Discover Nanome AI v2.1.0, featuring a unified Workspace API for seamless XR-web data sync, intuitive multi-structure interactions, advanced protein alignment, and immersive ligand evaluation.

Discover how Nanome XR enhances LiveDesign Live Reports by transforming 2D molecular insights into immersive 3D collaboration. Boost scientific innovation, spatial understanding, and remote teamwork in drug discovery.

Discover how MARA’s updated workflow system dramatically improves scientific productivity. With step-by-step planning, natural language editing, and reusable workflows, teams save time and gain precise control over complex computational tasks.

Discover the latest Nanome AI February 2025 Update with XR v2.0.11 and MARA v0.16.1—enhancing collaboration, visualization, and security for structure-based drug discovery. Explore new features like Residue Labels, seamless workspace joining, device code login, Human-in-the-loop Planning, and chat-driven file sharing. Streamline molecular analysis and accelerate discovery with improved tools for ligand evaluation, workflow automation, and secure API management.

Discover Nanome, the ultimate interface for molecular design, computational chemistry, and drug discovery. Explore how spatial computing, AI, and VR revolutionize the way scientists interact with molecules to accelerate breakthroughs in biopharma and materials science.

Dive into Nanome’s transformative year—expanding its platform with new plugins, integrating with Apple Vision Pro, launching MARA and Nanome AI, and unveiling Nanome 2.0. Discover how these milestones are reshaping immersive, collaborative, and AI-powered scientific workflows, and get a glimpse of the future trends in spatial computing and cutting-edge reasoning models coming in 2025.

Discover the evolution of file and workflow management with Nanome 2.0. Learn how this cloud-native platform streamlines molecular design with intuitive Workspaces, real-time cloud autosave, and seamless XR integration. Unlock the future of scientific collaboration with AI-powered tools and Apple Vision Pro compatibility.

Discover how MARA supports drug hunters and computational chemists with seamless assay data analysis, IC50 calculations, pIC50 scaling, cluster analysis, and molecular visualization for advanced research and drug discovery

We're excited to announce our revamped documentation site, adding major new sections for MARA, a system for scientific informatics, and Nanome 2.0, the latest version of their XR platform. These updates offer detailed guides, technical documentation, and sample workflows to help users navigate and maximize the capabilities of the new tools. The site has also been restructured for better organization and easier access, with older content still available under a dedicated section for Nanome 1.x. The refreshed layout aims to enhance user experience by providing clearer and more comprehensive resources.

Dive into Nanome 2.0, a reimagined molecular visualization platform that’s setting new standards in computational chemistry, chemical informatics, and bioinformatics. With advanced molecular data handling, seamless cloud-based data persistence, and an optimized rendering engine built for mobile XR and Apple Silicon devices, Nanome 2.0 empowers scientists and researchers to explore complex molecular structures collaboratively and intuitively. Unlock deeper insights in drug discovery and scientific informatics with Nanome’s enhanced capabilities, designed for scalable performance and future scientific advancements. Experience Nanome 2.0—where innovation meets the next generation of molecular science.

1. Explore Nanome 2.0’s New Permissioning System for Secure Collaboration – Discover how Nanome 2.0’s advanced Permissioning System helps scientists securely manage workspaces with Viewer, Editor, and Owner roles, fostering structured collaboration in drug discovery workflows.

Discover Nanome 2.0’s New Scenes Menu for Enhanced Molecular Visualization – Dive into Nanome 2.0’s innovative Scenes Menu, a groundbreaking feature designed to streamline molecular structure management, foster seamless collaboration, and improve your drug discovery workflows. Explore how the Scenes Menu can elevate your scientific research.

We’re excited to announce the integration of MARA within Jupyter Notebooks, allowing users to enhance data exploration, automation, and computational workflows seamlessly. Jupyter Notebooks provide an interactive environment for coding and visualization, now with MARA's powerful backend processes. This integration boosts productivity, streamlines tasks, and enhances collaboration. Ready to try it? Sign up and get 50 free credits!

Discover the future of molecular exploration with Nanome AI, the next evolutionary leap in scientific informatics. Combining the advanced capabilities of Nanome 2.0 with MARA, our Molecular Analysis and Reasoning Assistant, Nanome AI revolutionizes how scientists interact with data and molecules. Available now in early access, you can explore groundbreaking tools, provide feedback, and shape the future of molecular research. Dive into intuitive AI-driven workflows, enhanced collaboration features, and cutting-edge visualization tailored for the latest in XR technology. Request early access and join us in accelerating scientific discovery.

MARA Public Beta showcases its powerful capabilities in cheminformatics workflows. In this example, a scientist creates a molecular library by modifying R-groups in a ligand obtained from a PDB file, with natural language input. The workflow involves downloading a ligand, displaying its labeled 2D structure, and generating new molecules by substituting specific R-groups (e.g., methyl, cyano, methoxyl) at a designated position. MARA then converts the modified SMILES strings to .SDF files for docking studies. This process simplifies batch modifications of molecular structures using natural language commands.

MARA is a powerful bioinformatics tool that streamlines data analysis, offering custom-built functionalities for researchers to query databases, interconvert file formats, and organize data for in-depth analysis. Its intuitive workflows allow users to find similar protein sequences, perform multiple sequence alignments, introduce mutations, and create rotamer libraries using simple commands. MARA reduces the need for multiple applications, making it a valuable tool for both experienced bioinformaticians and newcomers. It transforms complex biological data into actionable insights, accelerating discoveries in fields such as medicinal chemistry.

MARA Update 0.12.10 introduces new features to enhance both enterprise and public beta user experiences. Key updates include expanded Structure Viewer commands, a new tool for converting mmCIF to PDB. Additionally, the Synthetic Accessibility Scorer (SAScorer) tool has been improved for enterprise users. The update also brings various UI improvements and system enhancements to streamline workflows and improve research capabilities.

Learn how MARA's extensibility allows you to create custom tools tailored to your lab's specific needs, making complex workflows accessible to your entire organization. Whether you're a coding expert or new to tool development, MARA offers solutions to streamline your lab's data management and analysis processes.

Nanome and Collaborative Drug Discovery (CDD) have partnered to enhance drug discovery workflows by integrating molecular visualization, design, and data analysis. This collaboration combines CDD Vault's secure management of biological and chemical data with Nanome's MARA platform, which uses natural language to streamline scientific workflows. Together, they aim to improve data-driven decision-making and foster global collaboration in drug discovery.

We are excited to showcase an integration between MARA by Nanome and Collaborative Drug Discovery (CDD Vault). In this blog, we delve into a common workflow of drug discovery researchers, breaking down the key steps in the process of leveraging an online hosted database and the conversational interface MARA provides.

This blog post introduces an example workflow in the MARA Public Beta, a powerful tool designed to streamline Computer Aided Drug Design (CADD) and Structural Based Drug Design (SBDD) workflows. MARA simplifies the process of analyzing three-dimensional structures of biological macromolecules, which is crucial for drug discovery, understanding disease mechanisms, and developing therapeutic strategies. The post outlines a step-by-step MARA workflow, from loading AlphaFold structures and preparing proteins for docking to drawing and docking molecules, and sending results to the Nanome app for further analysis. MARA's natural language prompts significantly reduce task complexity, making it a valuable asset for CADD/SBDD scientists.

We're thrilled to announce the public beta launch of MARA, a groundbreaking scientific informatics platform designed to leverage natural language to help you manage and optimize your workflows. In this blog, we’ll take a deep dive into a few MARA tools currently in place, ready for you to explore and implement in your own projects. Whether you're looking to streamline your project management, automate repetitive tasks, or enhance team collaboration, MARA has a suite of solutions tailored to meet your needs.

Discover the groundbreaking MARA Public Beta: Nanome's latest innovation in scientific informatics! Join us as we unveil the enhanced capabilities of MARA, offering a unique blend of customizability and user-centric tools for scientists. Dive into our blog to explore how MARA can streamline your research workflows, get insights on securing free credits for early users, and learn about our commitment to privacy and secure deployments. Don't miss out on the opportunity to shape the future of scientific computing—try MARA, provide feedback, and customize your tools. Sign up now to transform how you approach scientific challenges with MARA!

Discover the latest enhancements in scientific collaboration with Nanome V1.24.6. Our new patch simplifies virtual meetings with improved room control, ensuring seamless participant positioning and visibility. Explore how these updates, including support for additional MOE fields and various bug fixes, revolutionize structural biology, protein engineering, and computational chemistry. Elevate your research and demonstrations in XR like never before. Read our blog for an in-depth look at these game-changing features.

Discover the future of molecular visualization and computational chemistry with Nanome on Apple Vision Pro. Explore our groundbreaking prototypes, NanoSpin and Calcflow, now available on the Vision App Store. Learn about our roadmap for the full integration of Nanome v2.x by the end of 2024, despite the new device’s unique challenges and external dependencies. Experience a new era of immersive scientific exploration with Nanome’s advanced applications tailored for the innovative Apple Vision Pro.

Explore the Q2 2024 update on MARA, the transformative platform reshaping scientific research with advanced LLM technologies. Since its introduction in December 2023, MARA has evolved rapidly, enhancing its ability to bridge the gap between traditional scientific inquiry and automated, intelligent data analysis. This blog post delves into the recent advancements and solutions to challenges such as bias mitigation, hallucination issues, and workflow optimization. Discover how MARA’s integration of Retrieval Augmented Generation and tool-equipped Agents empowers scientists to engage with internal databases and execute complex informatics tasks with unprecedented ease. Learn about the new functionalities added to the MARA platform, including enhanced SQL query templates, Python snippet integration, and direct interactions via API. Perfect for enterprises, MARA ensures data security behind your organization’s IT firewall, offering a scalable, reliable solution for driving scientific innovation. Stay tuned for use cases and feedback from early adopters that underscore MARA’s role as a game-changer in the world of scientific research

Explore the cutting-edge advancements in computational chemistry and drug discovery with Nanome 2.0, now seamlessly integrated with Apple Vision Pro. This post offers an exclusive first look at how Nanome, a pioneer in in silico techniques and CADD (Computer-Aided Drug Design) modeling, is transforming medicinal chemistry. Discover the enhanced capabilities of our web application that merges home.nanome.ai and vault.nanome.ai for superior file and license management, accessible both within and outside of XR environments. Learn about the potential of deeper integration with MARA, our AI-powered research assistant, and stay tuned for more updates on how Nanome continues to empower drug hunters and researchers globally. Join us to see how Nanome 2.0 and the Apple Vision Pro are setting new standards in the quest for innovative drug discovery solutions.

Introducing Calcflow on Apple Vision Pro by Nanome, a breakthrough in 3D graph visualization for both educational and industrial applications. Now available on the Vision App Store, Calcflow Vision offers an immersive platform for exploring complex two-variable functions with ease. Whether you're a student mastering mathematical concepts or a professional in need of advanced visualization tools, this app facilitates a deeper understanding of spatial data through interactive, hands-on manipulation of 3D graphs. Embrace the future of visualization technology with Calcflow Vision, designed to revolutionize STEM learning and industry practices alike.

Discover NanoSpin by Nanome, a groundbreaking app launched for Apple Vision Pro, designed to revolutionize the way we interact with molecules in the fields of medicinal chemistry, computational chemistry, drug discovery, pharmaceutical R&D, and structural biology. NanoSpin offers a unique 'lite' experience, setting the stage for the full integration of Nanome's platform with visionOS. This app allows users to engage with molecular structures, like caffeine or DNA, in an unprecedented, intuitive manner, leveraging the advanced spatial computing capabilities of the Apple Vision Pro. By introducing the concept of bounded volume apps, NanoSpin facilitates a seamless multitasking experience within a virtual environment, enhancing digital interactions beyond traditional AR/VR confines. A first in many regards, NanoSpin is not only compatible with all Apple devices but also introduces hands-free and eye-tracking interaction, marking a new era of immersive scientific exploration. As we look forward to expanding our Nanome platform on visionOS, NanoSpin serves as an exciting preview into the future of molecular design and scientific discovery. Download now from the App Store and step into the nanoscale world with ease and sophistication

Enhance your molecular storytelling with 'The Nanome Scene Viewer' by Sheila Zipfel. This blog introduces Nanome's latest innovation, allowing you to craft custom 3D galleries of molecular structures. Discover how to manipulate and present protein models like never before using Nanome’s Vault. Learn to arrange molecules in 3D space, add colors, labels, and highlight chemical interactions for impactful presentations. Save and share your creations for collaborative exploration and effective communication of structural narratives. Ideal for professionals in structural biology, cheminformatics, and drug discovery, the Nanome Scene Viewer offers a new dimension in molecular visualization and collaboration. Experience the power of interactive 3D presentations and transform how you share your scientific insights.

Revolutionize your molecular research with the Nanome Jupyter Cookbook Plugin. This blog delves into the innovative fusion of Python and Nanome's mixed reality, transforming the approach to molecular exploration. Discover the limitless possibilities of Python notebooks, collaborative XR sessions, and the power to create custom plugins for scientific research. Explore features like ligand binding pocket identification, molecular dynamics simulation, and seamless integration with internal tools. Ideal for professionals in drug discovery, computational medicinal chemistry, and structural biology, the Nanome Plugin Cookbook is your key to a new era of molecular discovery. Read insights from Simon J. Bennie, PhD., and step into the future of molecular research.

Discover the revolutionary impact of Apple's Vision Pro on mixed reality (MR) and scientific innovation in our latest blog post at Nanome. Dive into our detailed analysis of the Vision Pro's advanced features, including eye, hand, and voice-based controls, enhanced spatial computing, and seamless integration with the Apple ecosystem. Explore how this groundbreaking headset is set to redefine the boundaries of technology and productivity in MR, and how Nanome plans to leverage its capabilities for scientific breakthroughs.

Explore Nanome's 2023 reflections and 2024 projections in this insightful blog post. Discover the advancements in Mixed Reality (MR), the launch of groundbreaking devices like Meta Quest Pro and Apple Vision Pro, and the integration of Large Language Models (LLMs) in Nanome's innovative projects. Learn about the exciting developments in Nanome 2.0, the anticipated launch of Apple Vision Pro, and the expansion of MARA to a broader audience. Join us in looking forward to a transformative 2024, as we merge cutting-edge technology with science to create a real-life JARVIS for scientists.

Explore Nanome's MARA, a groundbreaking AI platform revolutionizing drug discovery and medicinal chemistry. This blog introduces MARA (Molecular Analysis and Reasoning Assistant), a cutting-edge tool designed to enhance the scientific informatics workflow in biopharma research. With its advanced AI and computational chemistry capabilities, MARA is a game-changer in drug discovery, offering personalized, conversational insights for complex cheminformatics tasks. As an adaptable, offline enterprise solution, it ensures secure, tailored integration in each lab. MARA's precision and reliability stand out, free from biases of pre-trained LLMs, and it's set for expansion in XR (AR/VR) platforms and diverse scientific fields. Anticipate a new era of interactive, immersive scientific research and development with MARA, embodying Nanome's vision of a real-life JARVIS for scientists. Dive into this transformative platform on Nanome's official page and explore its features, as reported by VentureBeat.

Important drugs such as Valium and Xanax function by affecting GABA (Gamma-Aminobutyric Acid), the main inhibitory neurotransmitter in the mammalian central nervous system. Professor Asher Brandt from University of Saint Joseph met Nanome scientists in virtual reality for a guided journey through the latest research on how the GABA-A receptor impacts pathological sleep in humans. Their session is now available on Youtube!

Collaborative work has become increasingly important in a variety of fields, from scientific research to design and engineering. However, working together remotely or in hybrid settings can be challenging, especially when it comes to XR environments. With the latest Nanome v1.24.4 patch, the platform has become even more user-friendly and streamlined for collaborative work. The new patch focuses on reducing the friction involved in setting up group sessions and loading content, making it easier and quicker than ever before to get started with collaborative work in Nanome. This improved functionality is set to revolutionize the way teams work together in XR, opening up new possibilities for research, design, and innovation. In this blog post, we'll explore the key improvements in the latest Nanome patch and how they will benefit users.

Discover the power of Nanome with its new innovative plugins and features designed to enhance drug discovery research. Explore Pymol integration, CryoEM, Antibody Representation, Conformer Generator, and more, alongside a seamless chat function and Quick Drop capabilities. Unlock new insights and drive breakthroughs in small molecule drug discovery, protein engineering, macromolecular design, and beyond with Nanome's cutting-edge tools.

The FDA recently approved Tzield, the first CD3-directed monoclonal antibody, which helps manage Type 1 Diabetes, and can delay the onset of symptoms by nearly three years. Nanome’s new VR plug-ins for biologics research make it easy for scientists to visualize, design, and simulate large molecules & complex biologics in 3D.

20 years and a vaccine for Lyme Disease is still in the works, but structural biology has another trick up its sleeve: Antibody Prophylaxis! We met with Dr. Mike Rudolph, senior scientist at NYSBC, in virtual reality to discuss his team's research on Lyme Disease.

AI is finally delivering on its promise to revolutionize drug discovery and development: a COVID-19 drug entirely designed by generative AI has been approved for human use and will soon begin clinical trials in China!

You can't catch a cold in virtual reality, but you can figure out how to stop the COVID-19 pandemic! Learn how scientists at the Oak Ridge National Laboratory designed an inhibitor for SARS-CoV-2 using virtual reality and a High Flux Isotope Reactor.

We’re thrilled to launch version 1.24 of Nanome alongside the Meta Quest Pro! Nanome 1.24 takes advantage of the Quest Pro’s hardware to deliver groundbreaking features such as Mixed Reality Passthrough for all-in-one devices, Meta Avatars, and more!

Toxic nerve agents have been used in war crimes, assassinations, and terrorist attacks. Thankfully, researchers at UCSD are leveraging virtual reality to develop antidotes. Virtual reality allows them to visualize acetylcholinesterase (AChE), the enzyme that nerve agents like sarin or VX attack.