[{"data":1,"prerenderedAt":531},["ShallowReactive",2],{"blog-post-nanome-classic-vs-nanome-v2":3,"blog-posts-nav":22},{"data":4,"meta":18},[5],{"id":6,"attributes":7},151,{"title":8,"content":9,"createdAt":10,"updatedAt":11,"publishedAt":12,"date":13,"description":14,"keywords":15,"slug":16,"category":17},"Nanome Classic and Nanome v2: what's different and where each feature lives","Nanome v2, which nanome.ai now calls simply Nanome, is the current app and the one to install on a [Quest 3 or 3S, Samsung Galaxy XR, Apple Vision Pro or a Windows PC over Meta Link](https:\u002F\u002Fhelp.nanome.ai\u002Fhelp\u002Fchoosinghardware). It's a [ground-up rebuild](https:\u002F\u002Fnanome.ai\u002Fblog\u002Fnanome-2.0:-a-deep-dive-into-the-technical-foundations) whose cloud workspaces also open in a browser at [app.nanome.ai](https:\u002F\u002Fnanome.ai\u002Fblog\u002Fthe-new-front-door-to-nanome), where MARA runs. Nanome Classic (v1.24) is the [previous generation](https:\u002F\u002Fnanome.ai\u002Fversions#classic). It [still runs](https:\u002F\u002Fnanome.ai\u002Fblog\u002Fthe-new-front-door-to-nanome), and it's the version for Stacks plugins and for headsets the current app doesn't target, such as Quest 2 and Quest Pro. The [versions page](https:\u002F\u002Fnanome.ai\u002Fversions) lists 2.6.1 as the current release, a free download from the [Meta Horizon Store](https:\u002F\u002Fwww.meta.com\u002Fexperiences\u002Fnanome-v2\u002F25124020873911281\u002F), and because the two apps have [separate store listings](https:\u002F\u002Fwww.meta.com\u002Fexperiences\u002Fnanome\u002F2038368596280231\u002F), one headset can carry both.\n\nBoth apps sign in to the same Nanome account. The [setup guide](https:\u002F\u002Fnanome.ai\u002Fsetup#network) lists one sign-in host for Classic and another for 2.6 and later, and home.nanome.ai handles accounts and licenses. When the current app opened to everyone on the Quest store, the [announcement](https:\u002F\u002Fnanome.ai\u002Fblog\u002Fnanome-v2.4.0:-early-access-release-mara-voice-commands-minimization-chem-interactions-and-more!) said paid license holders get it included during the early access period and log in with their existing credentials. Its store listing still carries the Early Access label.\n\n## Names that point at the same two apps\n\nStore listings, docs and older blog posts use different names for the same pair, and the [versions page](https:\u002F\u002Fnanome.ai\u002Fversions) files them under \"Current Nanome\" and \"Previous generation\".\n\n\u003Ctable class=\"table\">\n  \u003Cthead>\n    \u003Ctr>\u003Cth>Name you see\u003C\u002Fth>\u003Cth>Which app\u003C\u002Fth>\u003C\u002Ftr>\n  \u003C\u002Fthead>\n  \u003Ctbody>\n    \u003Ctr>\u003Ctd>Nanome, Nanome v2, Nanome 2.0\u003C\u002Ftd>\u003Ctd>The current app, 2.6.1 (\u003Ca href=\"https:\u002F\u002Fnanome.ai\u002Fversions\">versions\u003C\u002Fa>)\u003C\u002Ftd>\u003C\u002Ftr>\n    \u003Ctr>\u003Ctd>Nanome Classic, v1, Nanome 1.x, v1.24\u003C\u002Ftd>\u003Ctd>Classic (\u003Ca href=\"https:\u002F\u002Fnanome.ai\u002Fblog\u002Ffrom-vault-to-workspaces:-the-evolution-of-file-and-workflow-management-in-nanome-2.0\">1.x and 2.0 explained\u003C\u002Fa>)\u003C\u002Ftd>\u003C\u002Ftr>\n    \u003Ctr>\u003Ctd>\"Nanome v2\" on the Meta Horizon Store\u003C\u002Ftd>\u003Ctd>The current app (\u003Ca href=\"https:\u002F\u002Fwww.meta.com\u002Fexperiences\u002Fnanome-v2\u002F25124020873911281\u002F\">listing\u003C\u002Fa>)\u003C\u002Ftd>\u003C\u002Ftr>\n    \u003Ctr>\u003Ctd>\"Nanome\" on the Meta Horizon Store\u003C\u002Ftd>\u003Ctd>Classic, with its Python plugin system (\u003Ca href=\"https:\u002F\u002Fwww.meta.com\u002Fexperiences\u002Fnanome\u002F2038368596280231\u002F\">listing\u003C\u002Fa>)\u003C\u002Ftd>\u003C\u002Ftr>\n    \u003Ctr>\u003Ctd>\"Nanome\" on Steam, released 2018\u003C\u002Ftd>\u003Ctd>Classic for Windows PC VR (\u003Ca href=\"https:\u002F\u002Fstore.steampowered.com\u002Fapp\u002F493430\u002FNanome\u002F\">listing\u003C\u002Fa>)\u003C\u002Ftd>\u003C\u002Ftr>\n  \u003C\u002Ftbody>\n\u003C\u002Ftable>\n\nThe Steam listing is the easiest to misread, because it carries the plain name and the older date. It's Classic: the [versions page](https:\u002F\u002Fnanome.ai\u002Fversions#classic) lists Steam among Classic's stores and leaves it off the current app's.\n\n## Side by side\n\n\u003Ctable class=\"table\">\n  \u003Cthead>\n    \u003Ctr>\u003Cth>\u003C\u002Fth>\u003Cth>Nanome Classic (v1.24)\u003C\u002Fth>\u003Cth>Nanome (2.6.1)\u003C\u002Fth>\u003C\u002Ftr>\n  \u003C\u002Fthead>\n  \u003Ctbody>\n    \u003Ctr>\u003Ctd>Where work lives\u003C\u002Ftd>\u003Ctd>Workspaces saved by hand, plus the Vault plugin for cloud files\u003C\u002Ftd>\u003Ctd>Cloud workspaces inside projects, saved as you go (\u003Ca href=\"https:\u002F\u002Fnanome.ai\u002Fblog\u002Fnanome-2.0:-a-deep-dive-into-the-technical-foundations\">technical foundations\u003C\u002Fa>)\u003C\u002Ftd>\u003C\u002Ftr>\n    \u003Ctr>\u003Ctd>Sessions\u003C\u002Ftd>\u003Ctd>Rooms led by a presenter (\u003Ca href=\"https:\u002F\u002Fnanome.ai\u002Fblog\u002Fv1.24.6-patch-release\">room controls\u003C\u002Fa>)\u003C\u002Ftd>\u003Ctd>Spotlight and follow, with no designated presenter (\u003Ca href=\"https:\u002F\u002Fhelp.nanome.ai\u002Fnanome_v2\u002Fcollaboration\">collaboration docs\u003C\u002Fa>)\u003C\u002Ftd>\u003C\u002Ftr>\n    \u003Ctr>\u003Ctd>Without a headset\u003C\u002Ftd>\u003Ctd>A Windows 2D mode that can spectate but can't edit (\u003Ca href=\"https:\u002F\u002Fhelp.nanome.ai\u002Fhelp\u002Ffaq\">FAQ\u003C\u002Fa>)\u003C\u002Ftd>\u003Ctd>The full app in a browser at app.nanome.ai, in the same live session as headset users (\u003Ca href=\"https:\u002F\u002Fnanome.ai\u002Fblog\u002Fnanome-v2.5:-web-trajectories-torsion-tool-and-more\">web and XR together\u003C\u002Fa>)\u003C\u002Ftd>\u003C\u002Ftr>\n    \u003Ctr>\u003Ctd>Tools\u003C\u002Ftd>\u003Ctd>Stacks plugins (\u003Ca href=\"https:\u002F\u002Fnanome.ai\u002Fv1stacks\">Stacks\u003C\u002Fa>)\u003C\u002Ftd>\u003Ctd>Built-in tools plus MARA's 300+ tools (\u003Ca href=\"https:\u002F\u002Fnanome.ai\u002Fintegrations\">integrations\u003C\u002Fa>)\u003C\u002Ftd>\u003C\u002Ftr>\n    \u003Ctr>\u003Ctd>Headsets\u003C\u002Ftd>\u003Ctd>Quest 2, Quest Pro and Quest 3, Pico and Vive standalones, and PC VR (\u003Ca href=\"https:\u002F\u002Fhelp.nanome.ai\u002Fhelp\u002Fchoosinghardware-classic\">Classic hardware\u003C\u002Fa>)\u003C\u002Ftd>\u003Ctd>Quest 3\u002F3S, Galaxy XR, Vision Pro, plus PCVR through Meta Link (\u003Ca href=\"https:\u002F\u002Fhelp.nanome.ai\u002Fhelp\u002Fchoosinghardware\">hardware page\u003C\u002Fa>)\u003C\u002Ftd>\u003C\u002Ftr>\n  \u003C\u002Ftbody>\n\u003C\u002Ftable>\n\nThe file side of that change has its own write-up in [from Vault to workspaces](https:\u002F\u002Fnanome.ai\u002Fblog\u002Ffrom-vault-to-workspaces:-the-evolution-of-file-and-workflow-management-in-nanome-2.0).\n\n## Where each Classic plugin lives in Nanome\n\nThe [Stacks page](https:\u002F\u002Fnanome.ai\u002Fv1stacks) marks Stacks as compatible with v1.24 or below and sends v2 integrations through MARA. Most of the old plugins now have a built-in home, and the rest run as MARA tools. The last row, spatial recording, was built into Classic itself and has a new home as well.\n\n\u003Ctable class=\"table\">\n  \u003Cthead>\n    \u003Ctr>\u003Cth>In Classic\u003C\u002Fth>\u003Cth>Where it lives in Nanome 2.6.1\u003C\u002Fth>\u003C\u002Ftr>\n  \u003C\u002Fthead>\n  \u003Ctbody>\n    \u003Ctr>\u003Ctd>Structure Prep\u003C\u002Ftd>\u003Ctd>Cartoon is a built-in representation, and Secondary Structure is a color scheme (\u003Ca href=\"https:\u002F\u002Fhelp.nanome.ai\u002Fnanome_v2\u002Fmainpanel#representations-and-color-options\">Main Panel\u003C\u002Fa>). MARA's Clean Up PDB and PDB File Fixer tools handle messy files (\u003Ca href=\"https:\u002F\u002Fnanome.ai\u002Fintegrations\">integrations\u003C\u002Fa>).\u003C\u002Ftd>\u003C\u002Ftr>\n    \u003Ctr>\u003Ctd>Minimization\u003C\u002Ftd>\u003Ctd>Minimize in the Builder tool, on the molecule being built or edited, with MMFF94, MMFF94s or UFF (\u003Ca href=\"https:\u002F\u002Fhelp.nanome.ai\u002Fnanome_v2\u002Ftoolspanel#minimization\">Tools Panel\u003C\u002Fa>)\u003C\u002Ftd>\u003C\u002Ftr>\n    \u003Ctr>\u003Ctd>Chemical Interactions\u003C\u002Ftd>\u003Ctd>Structure Actions, then Create interaction components (\u003Ca href=\"https:\u002F\u002Fhelp.nanome.ai\u002Fnanome_v2\u002Fmainpanel#structure-actions\">Main Panel\u003C\u002Fa>)\u003C\u002Ftd>\u003C\u002Ftr>\n    \u003Ctr>\u003Ctd>Docking (AutoDock Smina)\u003C\u002Ftd>\u003Ctd>MARA's Smina docking tools (\u003Ca href=\"https:\u002F\u002Fnanome.ai\u002Fintegrations\">integrations\u003C\u002Fa>)\u003C\u002Ftd>\u003C\u002Ftr>\n    \u003Ctr>\u003Ctd>Superimpose Proteins and RMSD\u003C\u002Ftd>\u003Ctd>Structure Actions, then Align proteins to this, which reports RMSD for each aligned entry (\u003Ca href=\"https:\u002F\u002Fhelp.nanome.ai\u002Fnanome_v2\u002Fmainpanel#structure-actions\">Main Panel\u003C\u002Fa>)\u003C\u002Ftd>\u003C\u002Ftr>\n    \u003Ctr>\u003Ctd>Electrostatic Potential\u003C\u002Ftd>\u003Ctd>ESP surface coloring with custom color ramps (\u003Ca href=\"https:\u002F\u002Fnanome.ai\u002Fblog\u002Fnanome-v2.5:-web-trajectories-torsion-tool-and-more\">v2.5 notes\u003C\u002Fa>), and MARA's Run APBS tool (\u003Ca href=\"https:\u002F\u002Fnanome.ai\u002Fintegrations\">integrations\u003C\u002Fa>)\u003C\u002Ftd>\u003C\u002Ftr>\n    \u003Ctr>\u003Ctd>Chemical Properties and Data Table\u003C\u002Ftd>\u003Ctd>The Ligands tab, with RDKit properties and SDF metadata as columns (\u003Ca href=\"https:\u002F\u002Fhelp.nanome.ai\u002Fnanome_v2\u002Fmainpanel#ligands-tab\">Main Panel\u003C\u002Fa>)\u003C\u002Ftd>\u003C\u002Ftr>\n    \u003Ctr>\u003Ctd>Vault\u003C\u002Ftd>\u003Ctd>Workspaces, from the Workspaces tab or app.nanome.ai (\u003Ca href=\"https:\u002F\u002Fnanome.ai\u002Fblog\u002Ffrom-vault-to-workspaces:-the-evolution-of-file-and-workflow-management-in-nanome-2.0\">Vault to workspaces\u003C\u002Fa>)\u003C\u002Ftd>\u003C\u002Ftr>\n    \u003Ctr>\u003Ctd>Spatial recording (built into Classic)\u003C\u002Ftd>\u003Ctd>The Scenes panel (\u003Ca href=\"https:\u002F\u002Fhelp.nanome.ai\u002Fnanome_v2\u002Fscenespanel\">Scenes Panel\u003C\u002Fa>), plus scene recording and playback (\u003Ca href=\"https:\u002F\u002Fnanome.ai\u002Fversions\">release notes\u003C\u002Fa>)\u003C\u002Ftd>\u003C\u002Ftr>\n  \u003C\u002Ftbody>\n\u003C\u002Ftable>\n\n## Why Cartoon or Minimize can be missing in Classic\n\nOn a standalone headset, Classic hands 2 jobs to Stacks that its PC build does on its own. The [Classic hardware page](https:\u002F\u002Fhelp.nanome.ai\u002Fhelp\u002Fchoosinghardware-classic#capability-plugin-recommendation-comparison-nanome-classic-v1-24) strongly recommends the Structure Prep plugin for bonding and secondary structure on a Quest, where Windows needs no prep. Energy minimization runs through a cloud plugin on a Quest and on the CPU on Windows.\n\nSo a Quest without Stacks loses the plugin that adds the secondary structure Cartoon draws, and has nowhere to send a minimization. The same file opened in the PC build shows ribbons and minimizes locally.\n\nThe license can lock features too. Classic's 1.24.6 [release notes](https:\u002F\u002Fnanome.ai\u002Fversions#release-notes) list atom labels, surfaces, spatial playback and Duplicate Molecule as license-locked. In Nanome, Cartoon and [Minimize](https:\u002F\u002Fhelp.nanome.ai\u002Fnanome_v2\u002Ftoolspanel#minimization) are built in, so neither depends on a plugin.\n\n## Turning Stacks on in Classic\n\nPlugin access belongs to the Nanome account, and Classic's [release notes](https:\u002F\u002Fnanome.ai\u002Fversions#release-notes) reflect that: 1.19.2 fixed a plugin-list bug in rooms created by a user without plugins. Getting Stacks working takes 2 steps, one on each side.\n\n1. **Requesting it for the account.** Plugin requests go to support@nanome.ai, along with the account email that signs in to Classic. Which licenses include Stacks, and what it costs, is covered in [how much Nanome costs](https:\u002F\u002Fnanome.ai\u002Fblog\u002Fhow-much-does-nanome-cost).\n2. **Refreshing the headset.** After support confirms, the headset needs a fresh session: signing out of Classic, closing the app completely rather than leaving it in the background, and signing back in. The plugins show up in Classic's plugin list after that sign-in.\n\nIf the list still comes up empty, the network is the next suspect. Classic reaches Nanome-hosted plugins over TCP 8888 to plugins.nanome.ai, listed with its [network requirements](https:\u002F\u002Fnanome.ai\u002Fversions#classic), so a firewall that blocks that port keeps them from connecting.\n\n## Installing each app\n\nNanome comes from the Meta Horizon Store, where it's listed as Nanome v2, through an MDM, or as an APK from the [setup page](https:\u002F\u002Fnanome.ai\u002Fsetup#install). On Vision Pro it installs through TestFlight. It targets Quest 3 and 3S, and Nanome's hardware page sends [Quest 2 and Quest Pro to Classic](https:\u002F\u002Fhelp.nanome.ai\u002Fhelp\u002Fchoosinghardware#headsets-not-supported), even though the Nanome v2 store listing still names those two headsets among its platforms.\n\nClassic installs from the Meta Horizon Store, Vive Business or Steam, or as an APK or Windows installer from the [versions page](https:\u002F\u002Fnanome.ai\u002Fversions#classic).\n\nAn original Quest, sold as the Oculus Quest, runs neither. It [doesn't appear as a supported platform on any current Nanome store listing](https:\u002F\u002Fhelp.nanome.ai\u002Fhelp\u002Fchoosinghardware-classic#headsets-not-supported). The full device list is in [which VR headsets work with Nanome](https:\u002F\u002Fnanome.ai\u002Fblog\u002Fwhich-vr-headsets-work-with-nanome).\n\n## Custom plugins\n\nPlugins written for Classic's Python plugin system stay on Classic, since the [Stacks page](https:\u002F\u002Fnanome.ai\u002Fv1stacks) points v2 integrations to MARA, and [the post on getting MARA](https:\u002F\u002Fnanome.ai\u002Fblog\u002Fhow-to-get-mara-and-what-it-can-run) covers building custom tools there.\n\n## Moving a course from Classic to Nanome\n\nBecause the apps install side by side, a course needs no hard switch date. A cohort partway through the term can stay on Classic with Stacks on, while the next activity runs as a pilot in Nanome.\n\nStudents without a headset can join that pilot from a browser, because a [Free Web Seat](https:\u002F\u002Fnanome.ai\u002Fsetup#account) can watch a session without editing and holds up to 3 workspaces. Classic workspace files aren't on the current app's [supported formats list](https:\u002F\u002Fhelp.nanome.ai\u002Fnanome_web\u002Ffileformats), so structures move across as PDB, mmCIF or SDF.\n\n## FAQ\n\n**Does my license cover the current Nanome app?**\nYes for paid license holders while the current app is in early access, and its store listing still says Early Access. The [announcement](https:\u002F\u002Fnanome.ai\u002Fblog\u002Fnanome-v2.4.0:-early-access-release-mara-voice-commands-minimization-chem-interactions-and-more!) that opened it on the Quest store said v2 is included for them during that period and they log in with their existing credentials. New accounts start with a [14-day Full trial](https:\u002F\u002Fnanome.ai\u002Fsetup#account), and the current seats are on the [pricing page](https:\u002F\u002Fnanome.ai\u002Fpricing).\n\n**Nanome opens but does nothing on our license. What should we check?**\nThe headset first: the current app [targets Quest 3 and 3S](https:\u002F\u002Fhelp.nanome.ai\u002Fhelp\u002Fchoosinghardware#headsets-not-supported). Then the network: Nanome 2.6 and later sign in through api.nanome.com, while Classic uses api.nanome.ai ([setup guide](https:\u002F\u002Fnanome.ai\u002Fsetup#network)). A firewall that allows only the older host lets Classic sign in and keeps the current app from signing in. Last, the seat: the current app in a headset requires a [Collab or Full seat](https:\u002F\u002Fnanome.ai\u002Fsetup#account).\n\n**Was docking removed?**\nNo. It moved from a Stacks plugin into MARA, which runs Smina docking from the browser and, per the [integrations page](https:\u002F\u002Fnanome.ai\u002Fintegrations), from inside a headset too.\n\n**What replaced Vault, and who can see my files?**\nWorkspaces replaced it in the current app ([Vault to workspaces](https:\u002F\u002Fnanome.ai\u002Fblog\u002Ffrom-vault-to-workspaces:-the-evolution-of-file-and-workflow-management-in-nanome-2.0)). Each workspace has Owner, Editor and Viewer roles ([collaboration docs](https:\u002F\u002Fhelp.nanome.ai\u002Fnanome_v2\u002Fcollaboration#permissions)), and access by workspace code can be set to None, so only people invited by email get in ([Users tab](https:\u002F\u002Fhelp.nanome.ai\u002Fnanome_v2\u002Fmainpanel#permissions)). In Classic, Vault stays a Stacks plugin.\n","2026-10-03T03:47:17.102Z","2026-10-13T16:00:51.059Z","2026-10-13T16:00:51.002Z","2026-10-13","Nanome (v2) is the current app, Nanome Classic (v1.24) still runs, and both sign in to one Nanome account. A feature map, a naming guide and the Stacks fix.","","nanome-classic-vs-nanome-v2","frequent-topics",{"pagination":19},{"page":20,"pageSize":21,"pageCount":20,"total":20},1,100,{"data":23,"meta":528},[24,29,35,40,45,50,55,60,65,70,75,81,86,91,97,102,107,112,117,122,127,132,137,142,147,153,158,163,168,173,178,183,188,193,198,203,208,213,218,223,228,233,238,243,248,253,258,263,268,273,278,283,288,293,298,303,309,314,319,324,329,334,339,344,349,354,359,364,369,374,379,384,389,394,399,404,409,414,419,424,429,434,439,444,449,454,459,464,469,474,479,484,489,493,498,503,508,513,518,523],{"id":20,"attributes":25},{"slug":26,"title":27,"category":28},"spy-stories-and-rational-drug-design","Spy stories & rational drug design","case-studies",{"id":30,"attributes":31},2,{"slug":32,"title":33,"category":34},"meta-quest-pro-and-a-new-version-of-nanome-(v1.24)","Meta Quest Pro & a new version of Nanome (v1.24)","releases",{"id":36,"attributes":37},3,{"slug":38,"title":39,"category":28},"beating-the-pandemic-in-virtual-reality","Beating the Pandemic in Virtual Reality",{"id":41,"attributes":42},4,{"slug":43,"title":44,"category":28},"a-new-era-in-drug-discovery-the-first-ai-generated-drug-is-going-to-clinical-trial","A new era in drug discovery? The first AI-generated drug is going to clinical trial",{"id":46,"attributes":47},5,{"slug":48,"title":49,"category":28},"antibody-prophylaxis-for-lyme-disease","Antibody Prophylaxis for Lyme Disease",{"id":51,"attributes":52},6,{"slug":53,"title":54,"category":28},"diabetes-treatment-is-about-to-change-forever","Diabetes treatment is about to change forever",{"id":56,"attributes":57},7,{"slug":58,"title":59,"category":34},"april-2023-nanome-plugins-and-home.nanome.ai-updates","April 2023 Nanome Plugins & home.nanome.ai Updates",{"id":61,"attributes":62},8,{"slug":63,"title":64,"category":34},"v1.24.4-patch-release-blog-and-data-table-plugin-update","v1.24.4 Patch Release Blog and Data Table Plugin Update",{"id":66,"attributes":67},9,{"slug":68,"title":69,"category":28},"exploring-gaba-in-vr-common-therapeutics-can-reverse-pathological-sleep-conditions","Exploring GABA in VR - Common therapeutics can reverse pathological sleep conditions",{"id":71,"attributes":72},10,{"slug":73,"title":74,"category":34},"introducing-mara:-a-paradigm-shift-in-ai-assisted-scientific-informatics-workflow-orchestration","Introducing MARA: A Paradigm Shift in AI-assisted Scientific Informatics Workflow Orchestration",{"id":76,"attributes":77},11,{"slug":78,"title":79,"category":80},"reflecting-on-2023-and-looking-forward-to-2024","Reflecting on 2023, and looking forward to 2024","philosophy",{"id":82,"attributes":83},12,{"slug":84,"title":85,"category":80},"our-thoughts-on-the-up-and-coming-apple-vision-pro","Our thoughts on the up & coming Apple Vision Pro ",{"id":87,"attributes":88},14,{"slug":89,"title":90,"category":34},"introducing-the-the-nanome-scene-viewer-plugin","Introducing the The Nanome Scene Viewer Plugin",{"id":92,"attributes":93},13,{"slug":94,"title":95,"category":96},"revolutionize-your-research-with-the-nanome-jupyter-cookbook-plugin","Revolutionize Your Research with the Nanome Jupyter Cookbook 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